Scientific meeting NVRB
14-02-2014 - 14-02-2014
Location: Pieterskerkhof 23, 3512JS Utrecht
The meeting will be at Friday 14 february 2014. Location: Pieterskerkhof 23, 3512JS Utrecht
09.30 Coffee and Tea
09.55 Opening.
10.00 Małgorzata Krajewska (UMCG): ATR is essential for survival of homologous recombination-deficient tumors cells
10.15 Arlene Oei (AMC): PARP1-inhibition sensitizes combined hyperthermia–radiation and combined hyperthermia-cDDP treatment of cervical carcinoma cells
10.30 Peter Nagle (UMCG): Targeting DNA Repair to Enhance Particle Radiotherapy Treatment.
10.45 Marco Schaaf (Maastro lab): Evaluation of autophagy in response to ionizing irradiation and its influence on radiosensitivity.
Koffie break
11.15 Hanneke Stegeman (RadboudUMC): Improving chemoradiation efficacy in head and neck cancer patients by AKT inhibition
11.30 Ravi Narayan (VUMC): Targeting resistance to radio-chemotherapy by inhibition of the PI3Kinase-AKT signalling pathway
11.45 Tom Keulers (Maastro Lab): Targeting GABARAPL1, a hypoxia induced protein, after irradiation inhibits tumor regrowth.
12.00 Esther Kleibeuker (VUMC): Improving the radio-sensitizing effect of sunitinib by drug-specific scheduling.
Lunch + NVRB members meeting
13.15 KEYNOTE LECTURE : Fiona Stewart (NKI) Vascular effects after irradiation.
14.15 Bregje van Oorschot (AMC): Reduced Activity of DSB Repair Genes in Prostate Cancer Patients with Late Normal Tissue Radiation-Toxicity.
14.30 Martti Maimets (UMCG): Canonical Wnt/β-catenin pathway in salivary gland irradiation and regeneration.
14.45 Damiën van Berlo (NKI): Enhancing pre-clinical models to assess normal tissue toxicity of future radio-chemotherapy approaches
Pauze
15.15 Anika Nagelkerke (RadboudUMC): LAMP3 is involved in metastasis and therapy resistance in breast cancer.
15.30 Barry Jutten (Maastro lab): Autophagy inhibition abrogates the survival advantages of EGFRvIII+ cells, sensitizes tumors to irradiation and improves prognosis of GBM patients.
15.45 Rolf de Boer (UMCG): Rif1 localizes to ultrafine bridges during anaphase to maintain genomic integrity.
16.00 Nynke Hosper (UMCG): Radiation induced carcinogenesis of salivary and thyroid gland stem cells.
16.15 Laura van Dijk (RadboudUMC): HNSCC xenograft microSPECT 111In-cetuximab-F(ab’)2 and 18F-FDG PET imaging for early response monitoring after radiotherapy.
Klaas Breur Awards + Drinks